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1

Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector

Yajin Ni, Susan Sun, Ibe Oparaocha, Laurent Humeau, Brian Davis, Reuben Cohen, Gwendolyn Binder, Yung-Nien Chang, Vladimir Slepushkin, Boro Dropulic

Journal:

The Journal of Gene Medicine

Year:

2005

Language:

english

File:

PDF, 573 KB

english, 2005

2

Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol

Xiaobin Lu, Laurent Humeau, Vladimir Slepushkin, Gwendolyn Binder, Qiao Yu, Tatiana Slepushkina, Ziping Chen, Randall Merling, Brian Davis, Yung-Nien Chang, Boro Dropulic

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 398 KB

english, 2004

3

Culture of mouse brain capillary endothelial cell lines that express factor VIII, γ-glutamyl transpeptidase, and form junctional complexes in vitro

Boro Dropulić, Colin L. Masters

Journal:

In Vitro Cellular & Developmental Biology - Plant

Year:

1987

Language:

english

File:

PDF, 2.31 MB

english, 1987

4

A Virus Model for Examining the Intracellular Efficiency of a Ribozyme Targeted to HIV-1

Boro Dropulic, Kuan-Teh Jeang

Journal:

Year:

1993

File:

PDF, 471 KB

1993

5

Lentiviral Vectors: Their Molecular Design, Safety, and Use in Laboratory and Preclinical Research

Dropulić, Boro

Journal:

Human Gene Therapy

Year:

2011

Language:

english

File:

PDF, 208 KB

english, 2011

6

Rapid Generation of Stable Cell Lines Expressing High Levels of Erythropoietin, Factor VIII, and an Antihuman CD20 Antibody Using Lentiviral Vectors

Baranyi, Lajos, Doering, Christopher B., Denning, Gabriella, Gautney, Richard E., Harris, Kyle T., Spencer, H. Trent, Roy, Andre, Zayed, Hatem, Dropulic, Boro

Journal:

Human Gene Therapy Methods

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

7

Gene-Based Immunotherapy for Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome

Dropulic, Boro, June, Carl H.

Journal:

Human Gene Therapy

Year:

2006

Language:

english

File:

PDF, 200 KB

english, 2006

8

Gene therapy for Hunter syndrome: Prevention of neurocognitive deficit in MPS II mice by engraftment with lentiviral vector-transduced hematopoietic stem cells (HSC) but not with wild type HSC

McIvor, R. Scott, Podetz-Pedersen, Kelly, Nan, Zhenhong, Karlen, Andrea, Slepushkin, Vladimir, Roy, Andre, Yakovlev, Galina, Gong, Zi, Muenzer, Joseph, Dropulic, Boro

Journal:

Molecular Genetics and Metabolism

Year:

2013

Language:

english

File:

PDF, 66 KB

english, 2013

9

A Conditionally Replicating HIV-1 Vector Interferes with Wild-Type HIV-1 Replication and Spread

Boro Dropulić, Monika Hěrmánková and Paula M. Pitha

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.69 MB

english, 1996

10

Novel lentiviral vectors for human gene therapy

Journal:

Expert Opinion on Investigational Drugs

Year:

1998

Language:

english

File:

PDF, 62 KB

english, 1998

11

Gene Therapy for Human Immunodeficiency Virus Infection: Genetic Antiviral Strategies and Targets for Intervention

Dropulić, Boro, Jeang, Kuan-Teh

Journal:

Human Gene Therapy

Year:

1994

Language:

english

File:

PDF, 6.36 MB

english, 1994

12

Potent Inhibition of Simian Immunodeficiency Virus (SIV) Replication by an SIV-Based Lentiviral Vector Expressing Antisense Env

Braun, Stephen E., Lu, Xiaobin V., Wong, Fay Eng, Connole, Michelle, Qiu, Gang, Chen, Ziping, Slepushkina, Tatiana, Slepushkin, Vladimir, Humeau, Laurent M., Dropulic, Boro, Johnson, R. Paul

Journal:

Human Gene Therapy

Year:

2007

Language:

english

File:

PDF, 372 KB

english, 2007

13

Harnessing autophagy for cell fate control gene therapy

Felizardo, Tania C., Foley, Jason, Steed, Kevin, Dropulic, Boro, Amarnath, Shoba, Medin, Jeffrey A., Fowler, Daniel H.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.29 MB

english, 2013

14

[Advances in Pharmacology] Volume 30 || Activation and Inactivation of Gene Expression Using RNA Sequences

Year:

1994

Language:

english

File:

PDF, 1.41 MB

english, 1994

15

Lentiviral Vector Platform for Production of Bioengineered Recombinant Coagulation Factor VIII

Spencer, H Trent, Denning, Gabriela, Gautney, Richard E, Dropulic, Boro, Roy, Andre J, Baranyi, Lajos, Gangadharan, Bagirath, Parker, Ernest T, Lollar, Pete, Doering, Christopher B

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 943 KB

english, 2011

16

Culture of Mouse Brain Capillary Endothelial Cell Lines That Express Factor VIII, γ-Glutamyl Transpeptidase, and Form Junctional Complexes in vitro

Boro Dropulić and Colin L. Masters

Journal:

In Vitro Cellular & Developmental Biology

Year:

1987

Language:

english

File:

PDF, 1.50 MB

english, 1987

17

Entry of Neurotropic Arboviruses into the Central Nervous System: An in vitro Study Using Mouse Brain Endothelium

Boro Dropulic and Colin L. Masters

Journal:

The Journal of Infectious Diseases

Year:

1990

Language:

english

File:

PDF, 1.33 MB

english, 1990

18

Intracellular Susceptibility to Ribozymes in a Tethered Substrate—Ribozyme Provirus Model Is Not Predicted by Secondary Structures of Human Immunodeficiency Virus Type 1 RNAs in Vitro

DROPULIĆ, BORO, JEANG, KUAN-TEH

Journal:

Antisense Research and Development

Year:

1994

Language:

english

File:

PDF, 3.48 MB

english, 1994

19

Ribozymes: Use as Anti-HIV Therapeutic Molecules

DROPULIC, BORO, ELKINS, DAVID A., ROSSI, JOHN J., SARVER, NAVA

Journal:

Antisense Research and Development

Year:

1993

Language:

english

File:

PDF, 1004 KB

english, 1993

20

Concepts in Genetic Medicine || Gene Therapy for Cardiovascular Disease

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 144 KB

english, 2008

21

Concepts in Genetic Medicine || Nonviral Gene Delivery Systems

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 242 KB

english, 2008

22

648. Mitigating Tumor Escape: Tandem Anti-CD20- and CD19 SCFV-Based Chimeric Antigen Receptors (CARs) in Leukemia/Lymphoma

Xiong, Ying, Wu, Darong, Dropulic, Boro, Orentas, Rimas, Schneider, Dina

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 531 KB

english, 2016

23

532. Stable Transcriptional Repression, Gene Excision, and Parastism of HIV by Conditionally Replicating Lentiviral Vectors

Lopez-Lemus, Uriel A., Ackley, Amanda, Saayman, Sheena, Embree, Heather, Dropulic, Boro, Akkina, Ramesh, Charlins, Paige, Weinberg, Marc S., Morris, Kevin V.

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 293 KB

english, 2016

24

Concepts in Genetic Medicine || Lentivirus Vector Manufacturing

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 352 KB

english, 2008

25

Concepts in Genetic Medicine || Assays for the Quality Control of Lentiviral Vectors

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 431 KB

english, 2008

26

Concepts in Genetic Medicine || Assays for the Release of Cellular Gene Therapy Products

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 177 KB

english, 2008

27

Leukemia Cell Surface Antigen Modulation Induced By Dual CD19/CD20 Chimeric Antigen Receptor (CAR)-T Cells

Schneider, Dina, Xiong, Ying, Wu, Darong, Nolle, Volker, Schmitz, Sarah, Kaiser, Andrew, Dropulic, Boro, Orentas, Rimas

Journal:

Biology of Blood and Marrow Transplantation

Year:

2017

Language:

english

File:

PDF, 120 KB

english, 2017

28

Dual Targeted CD20/19 CAR-T Cell Production Using the ClinimacsÂ® Prodigy System

Shah, Nirav, Zhu, Fenlu, Xu, Huiqing, Schneider, Dina, Orentas, Rimas, Dropulic, Boro, Hari, Parameswaran, Keever-Taylor, Carolyn

Journal:

Biology of Blood and Marrow Transplantation

Year:

2017

Language:

english

File:

PDF, 352 KB

english, 2017

29

Concepts in Genetic Medicine || Genetically Modified T Cells for Human Gene Therapy

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 181 KB

english, 2008

30

Reference Standards for Gene and Cell Therapy Products

Dropulić, Boro

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 113 KB

english, 2017

31

A tandem CD19/CD20 CAR lentiviral vector drives on-target and off-target antigen modulation in leukemia cell lines

Schneider, Dina, Xiong, Ying, Wu, Darong, Nӧlle, Volker, Schmitz, Sarah, Haso, Waleed, Kaiser, Andrew, Dropulic, Boro, Orentas, Rimas J.

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2017

Language:

english

File:

PDF, 2.72 MB

english, 2017

32

Concepts in Genetic Medicine || Adeno-Associated Virus Vectors

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 123 KB

english, 2008

33

Concepts in Genetic Medicine || Assays for the Release of Viral Vector Gene Therapy Products for Human Clinical Trials

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 153 KB

english, 2008

34

Closed-system manufacturing of CD19 and dual-targeted CD20/19 chimeric antigen receptor T cells using the CliniMACS Prodigy device at an academic medical center

Zhu, Fenlu, Shah, Nirav, Xu, Huiqing, Schneider, Dina, Orentas, Rimas, Dropulic, Boro, Hari, Parameswaran, Keever-Taylor, Carolyn A.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.91 MB

english, 2017

35

Concepts in Genetic Medicine || Safety of Retroviral Vectors: Regulatory and Technical Considerations

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 211 KB

english, 2008

36

141 Phase I Trial of Genetically Modified Hematopoietic Progenitor Cells Facilitate Bone Marrow Chemoprotection and Enabling TMZ/O6BG Dose Escalation Resulting in Improved Survival

Sloan, Andrew E., Fung, Hua, Reese, Jane, Rogers, Lisa R., Murphay, Christopher, Lazrus, Hillard, Dropulic, Boro, Gerson, Stan L.

Journal:

Year:

2016

Language:

english

File:

PDF, 69 KB

english, 2016

37

The transfer of genetically engineered lymphocytes in melanoma patients: a Phase I dose escalation study

Regan, Courtney, Nishimura, Michael, Le Poole, I Caroline, Godellas, Constantine, Stiff, Patrick, Garrett-Mayer, Elizabeth, Li, Mingli, Shirai, Keisuke, Eby, Jonathan, Embree, Heather, Dropulic, Boro,

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 257 KB

english, 2015

38

Minimizing leukemia escape: implementing a dual anti-CD20- and CD19-scFv-based chimeric antigen receptor (CAR)

Schneider, Dina, Xiong, Ying, Roy, Andre, Kaiser, Andrew, Dropulic, Boro, Orentas, Rimas

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 212 KB

english, 2015

39

Stable Transcriptional Repression and Parasitism of HIV-1

Shrivastava, Surya, Charlins, Paige, Ackley, Amanda, Embree, Heather, Dropulic, Boro, Akkina, Ramesh, Weinberg, Marc S., Morris, Kevin V.

Journal:

Molecular Therapy — Nucleic Acids

Year:

2018

Language:

english

File:

PDF, 1.27 MB

english, 2018

40

A Unique Human Immunoglobulin Heavy Chain Variable Domain-Only CD33 CAR for the Treatment of Acute Myeloid Leukemia

Schneider, Dina, Xiong, Ying, Hu, Peirong, Wu, Darong, Chen, Weizao, Ying, Tianlei, Zhu, Zhongyu, Dimitrov, Dimiter S., Dropulic, Boro, Orentas, Rimas J.

Journal:

Frontiers in Oncology

Year:

2018

Language:

english

File:

PDF, 3.59 MB

english, 2018

41

Concepts in Genetic Medicine || Herpes Simplex Virus Vectors

Dropulic, Boro, Carter, Barrie J.

Year:

2008

File:

PDF, 796 KB

2008

42

Concepts in Genetic Medicine || The Manufacture of Adeno-Associated Viral Vectors

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 125 KB

english, 2008

43

Concepts in Genetic Medicine ||

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 6.55 MB

english, 2008

44

Concepts in Genetic Medicine ||

Dropulic, Boro, Carter, Barrie J.

Year:

2008

File:

PDF, 6.55 MB

2008

45

A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

Bari, Rafijul, Granzin, Markus, Tsang, Kam Sze, Roy, Andre, Krueger, Winfried, Orentas, Rimas, Pfeifer, Rita, Moeker, Nina, Verhoeyen, Els, Dropulic, Boro, Leung, Wing

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 1.43 MB

english, 2019

46

A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

Bari, Rafijul, Granzin, Markus, Tsang, Kam Sze, Roy, Andre, Krueger, Winfried, Orentas, Rimas, Pfeifer, Rita, Moeker, Nina, Verhoeyen, Els, Dropulic, Boro, Leung, Wing

Journal:

Frontiers in Immunology

Year:

2019

File:

PDF, 1.43 MB

2019

47

Concepts in Genetic Medicine || Lentivirus Vectors

Dropulic, Boro, Carter, Barrie J.

Year:

2008

Language:

english

File:

PDF, 225 KB

english, 2008

48

Concepts in Genetic Medicine || Lentivirus Vectors

Dropulic, Boro, Carter, Barrie J.

Year:

2008

File:

PDF, 225 KB

2008

49

Corrigendum: A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy

Bari, Rafijul, Granzin, Markus, Tsang, Kam Sze, Roy, Andre, Krueger, Winfried, Orentas, Rimas, Schneider, Dina, Pfeifer, Rita, Moeker, Nina, Verhoeyen, Els, Dropulic, Boro, Leung, Wing

Journal:

Frontiers in Immunology

Year:

2019

File:

PDF, 153 KB

2019